Integrative physiology of antidepressant drug action

Autoregulation of serotonin neurons: role in antidepressant drug action.

[Neuropsychological cognitive hypothesis of antidepressant drug action--literature review].

Depression is a state characterised by the psychobiological symptoms included in the international classifications. People suffering from depression, apart from the primary and auxiliary symptoms of this disorder, have specific emotional-cognitive schemas. They tend to interpret a neutral sign as a negative one more often. According to some researchers, using antidepressants can change an "auto...

Molecular & Integrative Physiology

Greetings from the Department of Molecular and Integrative Physiology (MIP). Phil Best resigned the MIP headship to take a position as associate dean of the College of Liberal Arts and Sciences (interrupted briefly by a tenure as interim dean) and I was appointed head of MIP in December, 2007. Phil guided the department for ten years during the interesting period following the reorganization of...

Pavlov and integrative physiology.

Ivan Petrovich Pavlov was the first physiologist to win the Nobel Prize. The Prize was given in 1904 for his research on the neural control of salivary, gastric, and pancreatic secretion. A major reason for the success and novelty of his research was the use of unanesthetized dogs surgically prepared with chronic fistulas or gastric pouches that permitted repeated experiments in the same animal...

Mathematical challenges in integrative physiology.

Traditional approaches to biomedical research are based on the subdivision of biological systems—by length (or time) scales (body, organ, tissue, cell, andmolecule), discipline (biology, physiology, bioengineering, etc.), or sub-systems (cardiovascular, musculoskeletal, gastrointestinal, etc.). These subdivisions, however, make it difficult to unravel the systemic nature of the mechanisms that ...